Abstract
A method of this invention for treating body tissues containing cancerous cells or non-malignant tumors with RF ablation, alone or in combination with systemic or localized chemotherapy comprising introducing a stylet comprising an electrode surface and a sleeve longitudinally moveable thereon into the vicinity of the body tissues, retracting the sleeve from a portion of the electrode surface, and supplying RF power to the electrode surface sufficient to heat the tissue to a temperature of above about 45.degree. C. for a time to cause reduction of tissue mass in the vicinity of the electrode. The RF power supplied to the electrode surface is sufficient to effect a desiccated fluid diffusion barrier capsule surrounding the body tissue being treated. The stylet can include a hollow tube having fluid distribution ports therein, and the method can include the step of passing fluid through one or more distribution ports into the body tissue being treated. The fluid can be saline...
Patent number: 5472441
Filing date: Mar 11, 1994
Issue date: Dec 5, 1995
Inventors: Stuart D. Edwards, Ronald G. Lax
Assignee: Zomed International
Primary Examiner: Michael Peffley
What is claimed is:
1. A method for ablating tissue at a tissue treatment site where dehydration of tissue at the tissue treatment site is reduced, the method comprising the steps of:
- a) introducing an Rf ablation device into a tissue treatment site, the device including a hollow tubular Rf electrode having a closed, sharpened distal tip, an electrode conductive surface for conducting Rf ablation, and a plurality of fluid distribution ports distributed along the length of the electrode for delivering chemotherapeutic agents to the tissue treatment site; and
- b) supplying Rf power to the electrode to produce a diffusion barrier capsule at the tissue treatment site wherein the position of the electrode relative to the tissue treatment site is varied sufficiently frequently to reduce dehydration of tissue at the tissue treatment site.
2. The method according to claim 1, further including the step of passing fluid through the fluid distribution ports during ablation to reduce dehydration of tissue at the tissue treatment site.
3. The method according to claim 1 further including the step of varying the position of the electrode relative to the tissue treatment site by at least 1 mm during ablation.
4. The method according to claim 2 further including the step of varying the position of the electrode relative to the tissue treatment site between about 1 and 3 mm.
5. The method according to claim 1 further including the step of varying the position of the electrode relative to the tissue treatment site along a longitudinal axis of the electrode.
6. The method according to claim 1 wherein the device further includes an electrode position modifier and further including the step of varying the position of the electrode relative to the tissue treatment site sufficiently frequently during ablation to reduce dehydration of tissue at the tissue treatment site.
7. The method according to claim 5 further including the step of passing fluid through the fluid distribution ports during ablation to reduce dehydration of tissue at the tissue treatment site.
8. The method according to claim 7 further including the step of varying the position of the electrode relative to the tissue treatment site is by at least 1 mm during ablation.
9. The method according to claim 8 further including the step of varying the position of the electrode relative to the tissue treatment site by between about 1 and 3 mm.
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